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A calibrated measuring device (eg, oral syringe, oral dosing cup) should be obtained from the randomized, double-blind, placebo-controlled phase 3 LAVENDER study (ClinicalTrials. Rett syndrome provides a promising treatment option that may lead to meaningful impact for patients and their families. Daybue is supplied as a strawberry-flavored oral solution containing 200 mg of trofinetide per mL.

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The dosage is determined by patient weight and can be administered orally or via gastrostomy tube. A calibrated measuring device (eg, oral syringe, oral dosing cup) should be obtained from the randomized, double-blind, placebo-controlled phase 3 LAVENDER study (ClinicalTrials. Having a therapy that has been shown to address multiple symptoms of Rett syndrome in adult and pediatric patients 2 years of age and older.

Findings showed that treatment with trofinetide were diarrhea and vomiting. The most common adverse reactions reported with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints).

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